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Image Search Results
Journal: Research Square
Article Title: NAPE-PLD in the ventral tegmental area regulates reward events, feeding and energy homeostasis
doi: 10.21203/rs.3.rs-3199777/v1
Figure Lengend Snippet: (A) Body weight and body composition of Napepld VTA-GFP and Napepld ΔVTA mice. (B-K) Indirect calorimetric studies in Napepld VTA-GFP and Napepld ΔVTA mice to assess energy balance and metabolic efficiency. Longitudinal measurements in calorimetric chambers of locomotor activity (B, B 1 ), food intake (C, C 1 ), energy expenditure EE (D, D 1 ), respiratory exchange ratio RER (E, E 1 ) and fatty acid oxidation FAO (F, F 1 ) in Napepld VTA-GFP and Napepld ΔVTA sated mice. (G-K) Indirect calorimetric studies in Napepld VTA-GFP and Napepld ΔVTA mice undergoing a fasting/refeeding metabolic challenge. (G) Locomotor activity, (H) cumulative food intake, (I) energy expenditure, (J) respiratory exchange ratio and (K) fatty acid oxidation. (L, M) Temporal kinetics and heatmaps of in vivo DA release dynamics in Napepld VTA-GFP and Napepld ΔVTA fasted mice and exposed to a chow pellet. Statistics: *p<0.05, **p<0.01 and ***p<0.001 for Napepld ΔVTA vs Napepld VTA-GFP mice. For number of mice/group and statistical details see Suppl. Table 1.
Article Snippet: Briefly, mice were monitored for whole energy expenditure (EE), O 2 consumption, CO 2 production, respiratory exchange rate (RER = VCO 2 /VO 2 , V = volume), and locomotor activity using
Techniques: Activity Assay, In Vivo
Journal: Research Square
Article Title: NAPE-PLD in the ventral tegmental area regulates reward events, feeding and energy homeostasis
doi: 10.21203/rs.3.rs-3199777/v1
Figure Lengend Snippet: (A, A 1 ) Time-locked (30 min/session) access to running wheels to mimic the reinforcing properties of exercise. (B-H) Indirect calorimetric studies in calorimetric chambers equipped with running wheels to assess energy balance and metabolic efficiency in Napepld VTA-GFP and Napepld ΔVTA mice. (B, B 1 ) Spontaneous locomotor activity, (C, C 1 ) running wheel activity, (D) total locomotor activity (spontaneous + running wheel activities), (E, E 1 ) energy expenditure, (F) cumulative food intake, (G) respiratory exchange ratio and (H) fatty acid oxidation. Statistics: *p<0.05, **p<0.01 and ***p<0.001 for Napepld ΔVTA vs Napepld VTA-GFP mice. For number of mice/group and statistical details see Suppl. Table 1.
Article Snippet: Briefly, mice were monitored for whole energy expenditure (EE), O 2 consumption, CO 2 production, respiratory exchange rate (RER = VCO 2 /VO 2 , V = volume), and locomotor activity using
Techniques: Activity Assay